abstract：:This review examines the appropriate timing of intervention in acute pancreatitis. In gallstone pancreatitis, it is now clear that cholecystectomy during the primary admission carries no greater risk of complications than delayed cholecystectomy and enables earlier recovery to normal activity. This course of action pr...

journal_title：Postgraduate medical journal

authors： Johnson CD

更新日期：1993-07-01 00:00:00

abstract：:A 12 year old boy presenting with hypercalcaemia (calcium 3.25 mmol/l) and osteopaenia with multiple osteolytic lesions was found to have acute lymphoblastic leukaemia without lymph-adenopathy or organomegaly. Hypercalcaemia is a rare feature of acute leukaemia, but the patients previously described all show very simi...

journal_title：Postgraduate medical journal

authors： Soni PN

更新日期：1993-06-01 00:00:00

abstract：:This paper reviews the current literature concerning the different investigative modalities available to assess the microcirculation in diabetic microangiopathy. The advantages and disadvantages of the different invasive and noninvasive methods available are presented objectively. We have concentrated on the tests tha...

journal_title：Postgraduate medical journal

authors： Chittenden SJ,Shami SK

更新日期：1993-06-01 00:00:00

abstract：:Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing disti...

journal_title：Postgraduate medical journal

authors： Carder PJ,Gouldesbrough DR

更新日期：1993-05-01 00:00:00

abstract：:There is considerable evidence to suggest that the identification and treatment of dyslipidaemia will reduce the risk of premature CHD, i.e. before the age of 65. Diagnosis of the cause of raised plasma lipid levels will enable appropriate decisions to be taken with regard to management. The cornerstone of treatment i...

journal_title：Postgraduate medical journal

authors： Betteridge DJ,Dodson PM,Durrington PN,Hughes EA,Laker MF,Nicholls DP,Rees JA,Seymour CA,Thompson GR,Winder AF

更新日期：1993-05-01 00:00:00

abstract：:We report a 44 year old man who developed external ophthalmoplegia and predominantly respiratory, truncal and bulbar weakness with brisk reflexes, histological evidence of an inflammatory myopathy and a high titre of acetylcholine receptor antibodies, one month after starting hydroxyurea and allopurinol for chronic my...

journal_title：Postgraduate medical journal

authors： Bergin PS,Gale AN

更新日期：1993-04-01 00:00:00

abstract：:Two sisters suffered from thrombotic thrombocytopenic purpura late in their first pregnancies. HLA typing of the patients and their immediate family members demonstrated no obvious relationship. Hereditary aspects, association with pregnancy, prognosis and management of pregnant women with TTP are discussed. ...

journal_title：Postgraduate medical journal

authors： Alqadah F,Zebeib MA,Awidi AS

更新日期：1993-03-01 00:00:00

abstract：:Acute loss of vision and alcoholic intoxication suggests the possibility of methanol poisoning. In this report we describe an alcoholic patient who complained of blindness after recovering from alcoholic pancreatitis and delirium tremens. Visual acuity was severely impaired and fundoscopy revealed florid bilateral cot...

journal_title：Postgraduate medical journal

authors： Steel JR,Cockcroft JR,Ritter JM

更新日期：1993-02-01 00:00:00

abstract：:Patient preference for intravenous or subcutaneous heparin in the treatment of deep venous thrombosis was assessed in a randomized cross-over study. Twenty patients with venographically proven deep venous thrombosis were randomized to receive subcutaneous or intravenous heparin for 3 days followed by 3 days of the oth...

journal_title：Postgraduate medical journal

authors： Robinson AM,McLean KA,Greaves M,Channer KS

更新日期：1993-02-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) has emerged worldwide as a significant and difficult-to-treat source of nosocomial infection, emphasizing the ever-present need for reliable and effective antisepsis. Betadine Solution (10% povidone-iodine; PVP-I) and Betadine Cream (5% povidone-iodine) are broad-spec...

journal_title：Postgraduate medical journal

authors： Goldenheim PD

更新日期：1993-01-01 00:00:00

abstract：:Catheter related sepsis, especially with staphylococci, is one of the most important complications of haemodialysis or peritoneal dialysis. In a prospective, randomized, open study of 129 haemodialysis patients, exit site infection and bacteraemia were significantly greater in the untreated group (18.2% each) than the...

journal_title：Postgraduate medical journal

authors： Fong IW

更新日期：1993-01-01 00:00:00

abstract：:A female patient demonstrating a previously not reported constellation of polyglandular autoimmune syndrome type III (including autoimmune thyroiditis, Graves' ophthalmopathy, insulin-dependent diabetes mellitus and vitiligo), coeliac disease and sarcoidosis is described. This may be a random association but might als...

journal_title：Postgraduate medical journal

authors： Papadopoulos KI,Hallengren B

更新日期：1993-01-01 00:00:00

abstract：:Rectal swabs obtained from 10 of 49 chronic-care geriatric patients were positive for Clostridium difficile, for a prevalence rate of 20.4%. Simultaneous sampling of 29 patients in an acute geriatric ward revealed four colonized patients, for a prevalence rate of 13.7%. A prospective study of C. difficile colonization...

journal_title：Postgraduate medical journal

authors： Rudensky B,Rosner S,Sonnenblick M,van Dijk Y,Shapira E,Isaacsohn M

更新日期：1993-01-01 00:00:00

abstract：:We describe the occurrence of primary hyperaldosteronism in two sisters. Although this is only the second published report of familial Conn's syndrome, it does have implications for the relatives of patients with Conn's syndrome and these are discussed. ...

journal_title：Postgraduate medical journal

authors： London N,Swales J,Hollinrake K,Bell P,Heagerty A

更新日期：1992-12-01 00:00:00

abstract：:In 91 patients with bronchiectasis seen over 6 years, a positive mycobacterial culture was obtained in 12 cases (13%). The organisms isolated were Mycobacterium tuberculosis in nine cases, Mycobacterium avium in two cases and Mycobacterium tuberculosis and chelonei were obtained on separate occasions in one case. Comp...

journal_title：Postgraduate medical journal

authors： Chan CH,Ho AK,Chan RC,Cheung H,Cheng AF

更新日期：1992-11-01 00:00:00

abstract：:Common bile duct perforation causing biliary peritonitis is an unusual entity and a pancreatic calculus causing this perforation is all the more rare, and to our knowledge has not been reported previously. Such an unusual presentation of chronic calcific pancreatitis is herein reported. ...

journal_title：Postgraduate medical journal

authors： Kumar A,Kataria R,Chattopadhyay TK,Karak PK,Tandon RK

更新日期：1992-10-01 00:00:00

abstract：:Hypercalcaemia occurs in up to 80% of patients with adult T-cell leukaemia-lymphoma (ATLL) associated with human T-cell leukaemia virus-1 infection. Elevated serum levels of 1,25-dihydroxycholecalciferol, implicated in the pathogenesis of hypercalcaemia in lymphoma, and of parathyroid hormone-related protein (PTHrP), ...

journal_title：Postgraduate medical journal

authors： Johnston SR,Hammond PJ

更新日期：1992-09-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：:A 63 year old woman had been intensively treated for recurrent carcinoma of the neck. Following acute vascular surgery of the carotid artery, she developed the vasodilatory type of the carotid sinus syndrome. The presentation of this type of the syndrome was remarkable, since it is usually associated with primary or m...

journal_title：Postgraduate medical journal

authors： Dees A,Baatenburg de Jong RJ,Meeuwis CA,de Boer MF,de Leeuw PW

更新日期：1992-06-01 00:00:00

abstract：:Colonoscopies performed in patients aged 80 years or older at the Sheba Medical Center were analysed according to the primary indication for the procedure: 101 colonoscopies were performed because of rectal bleeding of at least 2 months duration, and 335 for all other indications. Carcinoma of the large bowel was foun...

journal_title：Postgraduate medical journal

authors： Bat L,Pines A,Shemesh E,Levo Y,Zeeli D,Scapa E,Rosenblum Y

更新日期：1992-05-01 00:00:00

abstract：:We report a case of adult pyloric obstruction caused by the delayed presentation of a congenital gastric diverticulum. The derivation, classification and treatment of these abnormalities are discussed. ...

journal_title：Postgraduate medical journal

authors： Hale PC,O'Flynn WR

更新日期：1992-04-01 00:00:00

abstract：:Lymphocyte adenosine deaminase (L-ADA) activity, a measure of lymphocyte activity, was estimated in 10 healthy controls and 30 patients with typhoid fever (20 uncomplicated and 10 complicated) at the time of admission, at onset of complications and weekly until recovery. Mean L-ADA activity in healthy controls was 20....

journal_title：Postgraduate medical journal

authors： Khosla SN,Kumar D,Singh V

更新日期：1992-04-01 00:00:00

abstract：:Two patients with sarcoidosis and glomerular mesangial proliferative lesions are described. Although a causative relationship between sarcoidosis and glomerulonephritis has been suggested, critical review of the literature fails to confirm this. ...

journal_title：Postgraduate medical journal

authors： Howard RS,Gabriel R

更新日期：1992-03-01 00:00:00

abstract：:Tuberculous infection of the oesophagus is rare. This is confirmed by our present review of cases managed in our teaching hospitals over a period of 18 years which uncovered only 11 patients. The main presentation is that of dysphagia whose algorithm of investigation should seek to differentiate tuberculosis from carc...

journal_title：Postgraduate medical journal

authors： Mokoena T,Shama DM,Ngakane H,Bryer JV

更新日期：1992-02-01 00:00:00

abstract：:Erythromelalgia is an unusual condition characterized by attacks of burning pain in the hands and feet with local congestion and increased skin temperature. We report a case of erythromelalgia, with transient hypertension and elevated urinary catecholamines successfully treated by hypnotherapy. Such an association has...

journal_title：Postgraduate medical journal

authors： Chakravarty K,Pharoah PD,Scott DG,Barker S

更新日期：1992-01-01 00:00:00

abstract：:Using the WHO/ISFC definition and recommendations of nomenclature for cardiomyopathies, the aetiology is unknown. Over many years research has concentrated on defining pathogenetic mechanisms and owing to the widespread use of the bioptome-permitting recovery of fresh endomyocardial tissue-myocarditis has emerged as b...

journal_title：Postgraduate medical journal

authors： Olsen EG

更新日期：1992-01-01 00:00:00

abstract：:Although the relationship between group A streptococcal upper respiratory tract infection and the development of acute rheumatic fever has been known for many years, the pathogenetic mechanism(s) have never been defined. Thus, the mechanism of damage to the valves and to the myocardium in patients with rheumatic fever...

journal_title：Postgraduate medical journal

authors： Kaplan EL

更新日期：1992-01-01 00:00:00

abstract：:Two different doses of cefaclor advanced formulation (AF), a new sustained-release formulation of cefaclor, were compared with the regular formulation of cefaclor for efficacy and safety in the treatment of uncomplicated cystitis and asymptomatic bacteriuria. A 7-day course of treatment was used, and the trials were d...

journal_title：Postgraduate medical journal

authors： Hamilton-Miller JM,Iravani A,Brumfitt W,Byers KS,Dere WH

更新日期：1992-01-01 00:00:00

abstract：:Although an extensive literature exists on factors controlling sodium excretion in animal experimental models of heart failure, the relevance of these to the human condition remains largely unexplored. Increased renal sympathetic stimulation is considered responsible for heightened urinary sodium retention. Stimulatio...

journal_title：Postgraduate medical journal

authors： Good J,Frost G,Oakley CM,Cleland JG

更新日期：1992-01-01 00:00:00

abstract：:This study examines clinical features of late onset anorexia nervosa. This involved the scrutiny of a large database of patients with anorexia nervosa comprising data gathered at standardized initial assessments over the period 1960-1990. Patients with a late onset were compared to other selected patient samples. The ...

journal_title：Postgraduate medical journal

authors： Joughin NA,Crisp AH,Gowers SG,Bhat AV

更新日期：1991-11-01 00:00:00

abstract：:Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whet...

journal_title：Postgraduate medical journal

authors： Aydintug AO,Cervera R,D'Cruz D,Ramírez G,Asherson RA,Khamashta MA,Hughes GR

更新日期：1991-11-01 00:00:00

abstract：:Rectal (both digital and rigid sigmoidoscopic) examination is an important part of the clinical examination. The aim of this study was to find out the opinions of the patients to this routine examination at the time of referral by their general practitioner and during their first hospital interview. Assessment of the ...

journal_title：Postgraduate medical journal

authors： Ng DP,Mayberry JF,McIntyre AS,Long RG

更新日期：1991-10-01 00:00:00

abstract：:A 63 year old man who suffered from syringomyelia related to post-meningitic spinal arachnoiditis caused by Candida tropicalis is reported. The clinical syndrome of syringomyelia developed gradually and a definite diagnosis was delayed for more than 10 years. The patient has partially recovered after surgical treatmen...

journal_title：Postgraduate medical journal

authors： Phanthumchinda K,Kaoropthum S

更新日期：1991-08-01 00:00:00

abstract：:Haemorrhage of small bowel origin may prove to be a clinical and diagnostic challenge, particularly when the bleeding is massive and continuous. Such a case is described where the source of blood loss was a jejunal vascular abnormality. ...

journal_title：Postgraduate medical journal

authors： Saunders MP

更新日期：1991-07-01 00:00:00

abstract：:Both acute myocardial infarction and reperfusion therapy with thrombolytic agents may be associated with bradyarrhythmias, and there may be a case for 'prophylactic' insertion of a temporary pacing wire in selected patients. We describe 4 patients in whom clinical decisions had to be made concerning the appropriatenes...

journal_title：Postgraduate medical journal

authors： Lim CW,Bennie MJ,Lim R

更新日期：1991-07-01 00:00:00

abstract：:This is a case report of a 67 year old man who presented with a fluctuating level of consciousness and myoclonic jerks caused in part by hypercalcaemia. The diagnosis of cerebral neoplastic angioendotheleosis was only made later on brain biopsy and is the first report of the occurrence of hypercalcaemia in neoplastic ...

journal_title：Postgraduate medical journal

authors： Wierzbicki AS,Gibbs JM,Lidov HG,Lolin Y,Thomas PK

更新日期：1991-06-01 00:00:00

abstract：:Twelve healthy volunteers took part in a randomised, double-blind, balanced, cross-over study to investigate the effect of misoprostol on the pharmacokinetics of propranolol. The subjects took propranolol 80 mg twice daily by mouth plus either misoprostol 400 micrograms twice daily or placebo by mouth for 14.5 days, f...

journal_title：Postgraduate medical journal

authors： Bennett PN,Fenn GC,Notarianni LJ,Lee CE

更新日期：1991-05-01 00:00:00

abstract：:An 8 month old Caucasian girl, with congenital central alveolar hypoventilation syndrome (Ondine's Curse), was discharged with her home ventilation managed by her parents. Her subsequent neurophysical development assessed at 22 months of age was satisfactory. ...

journal_title：Postgraduate medical journal

authors： Chang YL,Meerstadt PW

更新日期：1991-05-01 00:00:00

abstract：:Percutaneous endoscopic gastrostomy (PEG) was performed on 28 elderly patients (mean age 82 years) who were dysphagic and intolerant of naso-gastric feeding. Twenty-six patients were recovering from a stroke; the interval between the onset of stroke and PEG averaged 63 days. The procedure was successful and well toler...

journal_title：Postgraduate medical journal

authors： Finucane P,Aslan SM,Duncan D

更新日期：1991-04-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00